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  • iPonatic – Portable Molecule Workstation

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    Brief

    Innovations in molecular assays—especially on the point-of-care testing (POCT) front—have spread this testing from molecular diagnostics laboratories into clinical microbiology laboratories—and now into general laboratories and even clinics and exam rooms.[1]   Access to sensitive and rapid infectious disease diagnostic assays is essential for accurate diagnosis, effective treatment, and timely infection control, making POCT vital to reducing TAT.  With novel POCT on the horizon, future studies are warranted to determine cost savings, antimicrobial usage, TAT, patient impact, and how to best implement in non-microbiology clinical laboratories and clinics.[2]   Sansure iPonatic (Portable Molecule Workstation) aims to innovate traditional diagnostic mode and assist precision diagnosis. It can provide quickly and convenient diagnosis experience for clinical emergency, health management, military safety, biological emergency and other applications.

    Core technologies

    • Rapid nucleic acid lysis at room temperature within 1 minute
    • Ultra fast amplification system in 8-45 minutes
    • Integrated automatic data analysis software
    • Results immediately printed by built-in printer

    Performance

    Diagnostic results consistent with international mainstream PCR instruments

    Parameters

    Model S-Q31A S-Q31B
    Detection platform Real-time PCR
    Detection module 1 amplification module 4 amplification modules
    Temperature control Liquid metal coated ceramic heating / Air cooling technology
    Heating rate ≥6.0℃ /s (from 50℃ to 95℃ )
    Cooling rate ≥2.0℃ /s (from 95℃ to 50℃ )
    Excitation light source LED
    Detector High sensitivity photodiode
    Applicable dyes FAM VIC ROX CY5
    Sensitivity Can detect single copy gene
    Electrical specification AC 100-200V 50/60Hz
    Dimension 230×284×376 mm (L×W×H) 336.5 × 280 × 435 mm (L×W×H)
    Weight 9.7Kg 13Kg
    Qualification CE

    Test menu

    Respiratory Infections : SARS-CoV-2, SARS-CoV-2/FluA/B, MP, ADV, BP.... HPV Infections : HrHPV, HPV 13+2, HPV 16/18, HPV 6/11.... Children's health : EBV, HCMV.... STIs : CT/UU/NG, CT, UU, NG, HSV-2.... Other test projects are under development  
    References
    [1].  Kozel TR, Burnham-Marusich AR. Point-of-care testing for infectious diseases: Past, present, and future. J Clin Microbiol 2017;55:2313-20.
    [2]. Paige M.K. Larkin,   Omai B. Garner. Molecular Point-of-Care Testing in Clinical Laboratories Laboratorians can lead a new era in rapid testing with expertise in quality control and result interpretation. Clinical Laboratory News. JUL.1.2020
  • MA-6000 Real-Time Quantitative Thermal Cycler

    Brief

    The MA-6000 Real-Time Quantitative Thermal Cycler has spent many years in the research and development phase, but it was worth the wait as this advanced technology will help you treat more patients and cut down your waiting times with its ability to process up to 96 samples at one time. Our new Real-Time fluorescence quantitative PCR system MA-6000 is equipped with innovative hardware, structure and optimised software to deliver higher quality results.

    Features

    Temperature Control Technology and Innovation MA-6000 employs a six independent temperature control module, associated with an infrared environmental scanning and monitoring system for temperature control and secured precision for the thermal block. A technologically designed thermal gradient customises twelve thermal conditions for multiple reaction actions in scientific research, maximising convenience for your research and scientific experiments. The MA-6000’s platinum sensor prevents temperature overshoot and undershoot, homogenised temperature variance which in tandem offer customers reliably excellent and repeatable data output.   The World's Leading Optical Detection Technology’s Built-In Advantages A world leading technology of optical conduction and detection is applied to MA-6000. A highly functional heat-resistance optical fibre conducts full-spectrum halogen light source to samples without attenuation. The emission fluorescence signals are synchronously collected by monochrome CCD, which together with its cooling system, physically eliminate dark current on the detection array. MA-6000 ensures extraordinary detection sensitivity, extends the application of thermal cycler from nucleic acid to biotinylated protein and expands a brand-new path for multiplex diagnosis in clinical field.

    Specifications

    PCR Module
    Sample capacity 96×200ul tubes / 12 x 8-well PCR strips / l x 96-well plate
    Temperature range 4-100 ℃
    Maximum ramp rate 3.5 ℃/s for heating; 3.2℃/s for cooling
    Temperature accuracy ± 0. 1 ℃
    Temperature uniformity ±0.25℃
    Temperature monitoring method 6 independent zones for temperature surveillance
    Gradient capability Yes
    Excitation light source Full spectrum halogen lamp(5 years warranty)
    Excitation spectrum 380-780nm
    Excitation channels Built-in 6(including I extension channels)
    Fluorescence dyes/probes FAM / SYBR Green I / VIC / HEX / TET / Cy3 / Cy3.5 / JOE / Yellow 555 / ROX / Texas Red / Cy5 / Cy5.5 / LC Red / Tamara
    Detection channels 96 two-way heat-resistance optical fibers
    Data resolution 5.000-10.000 copies with 99.8% confidence; 1.5 times differentiation for single reaction
    Thermo Cycler
    Power supply 100-240V
    Frequency 50-60Hz
    Dimensions(WxHxD)(cm) 54.8×38.8×28.8
    Weight 23kg
    Software Win7, Win8, Win10, etc.
    Qualification CE
  • SLAN-96P Real-Time PCR System

    Features

    Precise Temperature Control System: 1. The SLAN system adopts Peltier technology which can accurately and quickly control increases and decreases of temperature with a precision of ±0.1℃ and features long service life, no noise and no pollution, etc.; 2. Multiple-point temperature control technology ensures the uniformity between different wells. The temperature correction technology guarantees the accuracy of temperature and thus ensures the accuracy of assay result; 3. PCR tube temperature-control technology guarantees the accuracy of actual temperature of reagent in the tube and enables the SLAN to easily adjust for different reactions using different volumes.   Sensitive Photoelectric Detection System 1. High sensitivity photoelectric detector with no background noise which is fast and stable; 2. Lifetime maintenance-free ultra-bright LED cold light source with a large signal value and high stability; 3. Unique optical fiber conduction technology that greatly improves fluorescence collection efficiency and avoids fluorescence interference between neighboring tubes; 4. The system automatically selects best gain value for each tube without the need for user configuration. The SLAN®has an extremely broad measuring range for fluorescence; 5. Extremely high detection sensitivity with an extremely low fluorescence background value. It's not necessary for users to make optical correction or background correction.  

    SLAN-96P Multi-tasking Software Interface (analysis screen)

      Unique Electronic Automatic Hot Lid System 1. Flexible heating technology ensures uniform hot lid temperature; 2. The electronic automatic hot lid has an adjustment function for different 0.2ml reaction tubes to ensure even tube pressure; 3. Once the assay starts, the hot lid has automatic locking function to prevent assay failure following accidental opening.   Other functions
    · Power-off protection · Automatic saving result · Export of result
    · Real-time data display · Quantitative and qualitative analysis · File encryption
    · Automatic baseline optimization · Digital filtering · Search function
    · Report sheet print and edit · Melt curve function

    Specifications

    Product model SLAN-96P
    Sample capacity 96 wells (dual 48/48 reaction module)
    Sample size 15-50mL
    Consumable 0.2mL PCR tubes, 8-tube strips, 48-well plates
    Parallel running mode Dual reaction blocks/running 2 tests independently
    Temperature range 4-99°C
    Max ramp rate 4.0°C/sec
    Temperature accuracy ±0.1°C
    Temperature uniformity ±0.1°C
    Thermal cycling system Peltier-based system
    Temperature control mode Tube control/block control
    Light Source LED (maintenance-free)
    Detector High sensitivity photoelectric sensor
    Sensitivity 1 copy
    Linearity range 100-1010
    Resolution Can discriminate between 1000 copies and 2000 copies
    Excitation CH1 470nm    CH2 530nm    CH3 580nm CH4 630nm   CH5/CH6   custom-made
    Emission CH1 510nm    CH2 565nm    CH3 620nm CH4 665nm   CH5/CH6   custom-made
    Dyes and probes CH1 FAMTM /SYBRGreen®   CH2 VIC®/HEX/J0ETM /TET CH3 ROX/TexasRed®   CH4 CY5TM
    Hot-lid 30°C~108°C (default105°C, adjustable) electronic automatic hot-lid
    Power supply 230VAC, 50Hz
    Power consumption 850VA
    Dimensions 380mm x 520mm x 250mm (WxDxH)
    Weight 18Kg
    Communication RS232, USB
    Qualification CE
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